understand what effect sizes are and be able to interpret effect size.

  • Journal List
  • J Grad Med Educ
  • v.four(3); 2012 Sep
  • PMC3444174

J Grad Med Educ. 2012 Sep; 4(3): 279–282.

Using Effect Size—or Why the P Value Is Non Enough

Statistical significance is the least interesting thing most the results. Y'all should depict the results in terms of measures of magnitude –non just, does a treatment affect people, but how much does information technology affect them.

-Gene V. Glass one

The primary production of a enquiry inquiry is i or more than measures of upshot size, non P values.

-Jacob Cohen 2

These statements about the importance of effect sizes were made by two of the most influential statistician-researchers of the past one-half-century. All the same many submissions to Journal of Graduate Medical Educational activity omit mention of the effect size in quantitative studies while prominently displaying the P value. In this paper, we target readers with little or no statistical background in order to encourage you to meliorate your comprehension of the relevance of effect size for planning, analyzing, reporting, and understanding instruction research studies.

What Is Issue Size?

In medical education research studies that compare different educational interventions, effect size is the magnitude of the deviation between groups. The accented effect size is the difference between the average, or mean, outcomes in ii different intervention groups. For example, if an educational intervention resulted in the improvement of subjects' test scores by an average total of fifteen of l questions equally compared to that of some other intervention, the accented effect size is xv questions or three grade levels (30%) amend on the examination. Absolute effect size does not take into account the variability in scores, in that not every discipline achieved the average outcome.

In another case, residents' self-assessed confidence in performing a procedure improved an average of 0.four point on a Likert-type scale ranging from 1 to five, after simulation training. While the absolute effect size in the start example appears clear, the effect size in the 2d example is less apparent. Is a 0.4 modify a lot or trivial? Accounting for variability in the measured improvement may aid in interpreting the magnitude of the change in the second example.

Thus, issue size can refer to the raw difference betwixt group means, or absolute effect size, too as standardized measures of effect, which are calculated to transform the effect to an easily understood calibration. Accented event size is useful when the variables under study have intrinsic meaning (eg, number of hours of sleep). Calculated indices of effect size are useful when the measurements have no intrinsic meaning, such as numbers on a Likert scale; when studies have used unlike scales so no direct comparing is possible; or when effect size is examined in the context of variability in the population under written report.

Calculated effect sizes can also quantitatively compare results from unlike studies and thus are commonly used in meta-analyses.

Why Report Effect Sizes?

The effect size is the main finding of a quantitative report. While a P value tin inform the reader whether an consequence exists, the P value will not reveal the size of the effect. In reporting and interpreting studies, both the substantive significance (outcome size) and statistical significance (P value) are essential results to be reported.

For this reason, effect sizes should be reported in a paper'south Abstract and Results sections. In fact, an judge of the consequence size is often needed before starting the enquiry endeavor, in guild to calculate the number of subjects likely to be required to avoid a Blazon Ii, or β, error, which is the probability of final at that place is no effect when 1 actually exists. In other words, you must determine what number of subjects in the written report will be sufficient to ensure (to a detail caste of certainty) that the report has acceptable power to back up the null hypothesis. That is, if no departure is found betwixt the groups, then this is a true finding.

Why Isn't the P Value Enough?

Statistical significance is the probability that the observed divergence between two groups is due to chance. If the P value is larger than the blastoff level called (eg, .05), any observed difference is assumed to exist explained by sampling variability. With a sufficiently big sample, a statistical examination will almost always demonstrate a significant difference, unless there is no effect any, that is, when the effect size is exactly zero; yet very small differences, even if significant, are oftentimes meaningless. Thus, reporting only the pregnant P value for an analysis is not adequate for readers to fully understand the results.

For example, if a sample size is 10 000, a significant P value is likely to be found even when the deviation in outcomes betwixt groups is negligible and may not justify an expensive or time-consuming intervention over another. The level of significance past itself does not predict issue size. Different significance tests, upshot size is independent of sample size. Statistical significance, on the other manus, depends upon both sample size and effect size. For this reason, P values are considered to exist confounded because of their dependence on sample size. Sometimes a statistically significant result means only that a huge sample size was used.iii

A commonly cited case of this problem is the Physicians Health Study of aspirin to prevent myocardial infarction (MI).four In more than than 22 000 subjects over an boilerplate of 5 years, aspirin was associated with a reduction in MI (although not in overall cardiovascular mortality) that was highly statistically significant: P < .00001. The written report was terminated early due to the conclusive show, and aspirin was recommended for general prevention. Yet, the result size was very small: a risk departure of 0.77% with r 2  =  .001—an extremely modest effect size. Equally a effect of that written report, many people were advised to accept aspirin who would non experience benefit yet were as well at risk for adverse effects. Further studies found even smaller effects, and the recommendation to use aspirin has since been modified.

How to Calculate Event Size

Depending upon the type of comparisons under report, consequence size is estimated with dissimilar indices. The indices fall into two master report categories, those looking at effect sizes between groups and those looking at measures of association betwixt variables ( table one ). For 2 independent groups, outcome size tin exist measured by the standardized divergence between 2 means, or mean (grouping 1) – hateful (grouping 2) / standard difference.

Tabular array 1

Common Effect Size Indicesa

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The denominator standardizes the difference past transforming the absolute difference into standard deviation units. Cohen'south term d is an example of this type of outcome size alphabetize. Cohen classified effect sizes equally pocket-sized (d  =  0.2), medium (d  =  0.five), and large (d ≥ 0.8).5 According to Cohen, "a medium effect of .v is visible to the naked eye of a careful observer. A small effect of .two is noticeably smaller than medium only non then minor equally to be piffling. A large effect of .8 is the same altitude above the medium as small is below it."half dozen These designations large, medium, and small do not have into account other variables such as the accuracy of the assessment instrument and the diversity of the written report population. However these ballpark categories provide a full general guide that should as well be informed by context.

Between group means, the consequence size tin also be understood as the average percentile distribution of group one vs. that of group 2 or the amount of overlap betwixt the distributions of interventions 1 and 2 for the two groups nether comparison. For an issue size of 0, the mean of grouping two is at the 50th percentile of group 1, and the distributions overlap completely (100%)—that is , there is no difference. For an result size of 0.eight, the mean of group ii is at the 79th percentile of grouping 1; thus, someone from grouping 2 with an boilerplate score (ie, mean) would have a higher score than 79% of the people from group ane. The distributions overlap past only 53% or a non-overlap of 47% in this situation ( tabular array 2 ).5 , vi

TABLE ii

Differences between Groups, Effect Size measured by Glass's Δa

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What Is Statistical Ability and Why Practice I Need It?

Statistical power is the probability that your study will find a statistically significant difference betwixt interventions when an bodily difference does exist. If statistical power is high, the likelihood of deciding in that location is an effect, when one does be, is high. Power is 1-β, where β is the probability of wrongly concluding at that place is no effect when i really exists. This type of error is termed Blazon Two error. Like statistical significance, statistical ability depends upon effect size and sample size. If the result size of the intervention is large, it is possible to detect such an effect in smaller sample numbers, whereas a smaller effect size would require larger sample sizes. Huge sample sizes may detect differences that are quite pocket-size and possibly trivial.

Methods to increase the power of your report include using more potent interventions that have bigger effects, increasing the size of the sample/subjects, reducing measurement error (apply highly valid event measures), and raising the α level but simply if making a Type I error is highly unlikely.

How To Calculate Sample Size?

Before starting your written report, calculate the ability of your report with an estimated event size; if power is too depression, you lot may need more subjects in the study. How can you guess an effect size before carrying out the written report and finding the differences in outcomes? For the purpose of calculating a reasonable sample size, effect size can be estimated by pilot written report results, like work published by others, or the minimum deviation that would be considered of import by educators/experts. There are many online sample size/power calculators available, with explanations of their utilize (BOX).7 , viii

Box.  Calculation of Sample Size Case

Your pilot study analyzed with a Student t-test reveals that grouping 1 (N  =  29) has a hateful score of 30.one (SD, 2.8) and that group 2 (N  =  xxx) has a mean score of 28.5 (SD, 3.v). The calculated P value  =  .06, and on the surface, the divergence appears not significantly different. However, the calculated consequence size is 0.5, which is considered "medium" according to Cohen. In society to examination your hypothesis and determine if this finding is real or due to take a chance (ie, to find a pregnant difference), with an effect size of 0.5 and P of <.05, the ability will exist too low unless yous expand the sample size to approximately N  =  sixty in each group, in which example, ability volition reach .80. For smaller outcome sizes, to avoid a Type II fault, you would need to further increase the sample size. Online resource are available to help with these calculations.

Power must be calculated prior to starting the study; post-hoc calculations, sometimes reported when prior calculations are omitted, have limited value due to the incorrect assumption that the sample effect size represents the population effect size.

Of interest, a β error of 0.2 was chosen by Cohen, who postulated that an α error was more serious than a β error. Therefore, he estimated the β error at four times the α: 4 × 0.05  =  0.20. Although arbitrary, as this has been copied by researchers for decades, employ of other levels will need to be explained.

Summary

Effect size helps readers understand the magnitude of differences plant, whereas statistical significance examines whether the findings are likely to exist due to risk. Both are essential for readers to understand the total impact of your work. Written report both in the Abstract and Results sections.

Footnotes

Gail M Sullivan, Md, MPH, is Editor-in-Master, Journal of Graduate Medical Education; Richard Feinn, PhD, is Assistant Professor, Section Psychiatry, University of Connecticut Wellness Center.

References

i. Kline RB. Beyond Significance Testing: Reforming Data Assay Methods in Behavioral Research. Washington DC: American Psychological Association; 2004. p. 95. [Google Scholar]

ii. Cohen J. Things I take learned (so far) Am Psychol. 1990;45:1304–1312. [Google Scholar]

iv. Bartolucci AA, Tendera M, Howard G. Meta-analysis of multiple primary prevention trials of cardiovascular events using aspirin. Am J Cardiol. 2011;107(12):1796–801. [PubMed] [Google Scholar]

6. Coe R. It'south the upshot size, stupid: what "effect size" is and why it is important. Paper presented at the 2002 Almanac Briefing of the British Educational Research Association, University of Exeter, Exeter, Devon, England, September 12–14, 2002. http://world wide web.leeds.ac.uk/educol/documents/00002182.htm. Accessed March 23, 2012. [Google Scholar]


Articles from Journal of Graduate Medical Teaching are provided here courtesy of Accreditation Council for Graduate Medical Education


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Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444174/

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